Let's Combat Pain is a website designed as an open forum for patients to share experiences in a worldwide network. We encourage singles and patient groups to become active members in order to increase visibility and share experiences.
29 February 2012
Palmitoylethanolamide is an endogenous agonist for CB2-like receptors. Activation of such receptors may serve to downmodulate deleterious cellular processes following pathological events or noxious stimuli in both the nervous and immune systems. Cannabinoids, too, are agonist for CB2-like receptors.
On the road to knowledge, sometimes there are unexpected encounters…
27 November 2011
At last a new way to treat chronic pain without side effects, and via a whole new mechanism of action. This was the talk of the week last week in Naples, Italy. New data on the body own painkiller palmitoylethanolamide (Normast, PEA) were presented on Februari 9 and 10, 2012, at the congres on palmitoylethanolamide.
This congres focussed on biochemistry, pharmacology and therapeutic use of PEA, a pleiotropic anti-inflammatory lipid mediator. The congres was chaired by professor Vincenzo Di Marzo from the endocannabinoidresearch group from the institute of biomolecular chemistry, CNR, in Pozzuoli and professor Stephan Skraper from the university of Padua. More then 100 physicians and scientists all over the world participated to share and discuss new findings and insights.
PEA represents a revolution in the treatment of pain and inflammation, based on natural mechanisms to reduce pain and counteract inflammation, that have been biologically rippened during many million years of evolution in all mammals as well as in men.
This 'self treatment' is the base for what many doctor's always referred to as the natural healing tendency of our body. This always remained a vague intuitive notion, but since this age, we understand much better the biology of this self-healing mechanism and PEA plays a key role in this understanding and insight.
It was the famous neurologist professor Erminio Costa, who already in the last century, foresaw this new enfolding paradigm of healing, when he stressed that scientists developing new drugs, and doctors treating patients should ' follow were nature leads'.
More on: http://www.chronicpaincoalitio…..8;q=naples
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