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    Let's Combat Pain is a website designed as an open forum for patients to share experiences in a worldwide network. We encourage singles and patient groups to become active members in order to increase visibility and share experiences.
    On the "Ask The Expert" area a patient can ask for suggestions and information regarding his case.
    This site, the experts and participants will not provide diagnosis or prescribe medications. We strongly suggest that if needed you consult a professional entity.



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    Overcoming Opiophobia & Doing Opioids Right.
    8 November 2011
    Forum Posts: 8
    Member Since:
    6 November 2011

    A More Practical Perspective on Opioids,

    Commentary Author: Forest Tennant, MD, DrPH
    Most arguments against the use of opioids for a significant short-term or long-term
    pain problem are usually based on irrational fears, or so-called “opiophobia.”
    However, this ignores a more practical perspective.
    The only direct biologic pain-relief system in the human body is the
    endogenous opioid receptor system, consisting of endorphins and their tissue based
    action sites, or receptors. Any potent attack on pain must trigger or
    enhance this system. All other systems in the human body that may relieve pain
    must do it indirectly. Hence, pain treatment agents that exert their biologic effects
    by suppressing inflammation, blocking synapses or anion channels, or activating
    hormones for growth or healing must all act indirectly.Only opioids go to the heart of the matter, which is the endogenous opioid receptor system. When pain is severe, whether acute or chronic, indirect treatment agents such as anti-inflammatory or neuro-synaptic blocking agents may not only fail to adequately control pain, they may produce significant complications.
    Astonishingly, there is still widespread belief that pain is merely a psychological
    phenomenon with no inherent physical complications of its own, and aggressive
    medical treatment is, therefore, unwarranted. For example, some drug
    detoxification centers promote the self-serving concept that withdrawal from
    opioids can cure pain.
    While some rare forms of pain may be purely psychic manifestations, the
    notion that opioids should be withheld from a patient with severe pain in favor of
    various psychological, behavioral, or physical therapies is folly and dangerous.
    The scientific literature and extensive clinical experience abundantly demonstrate
    that the failure to adequately treat severe acute or chronic pain may produce a plethora
    of serious complications, including death from pain-related cardiovascular collapse.

    "quoted with permission of Dr. Tennant" to read full text go here …

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